PATHOGENETIC MECHANISMS OF LEPTIN RESISTANCE
نویسندگان
چکیده
منابع مشابه
Mechanisms of leptin action and leptin resistance.
The adipose tissue-derived hormone leptin acts via its receptor (LRb) in the brain to regulate energy balance and neuroendocrine function. LRb signaling via STAT3 and a number of other pathways is required for the totality of leptin action. The failure of elevated leptin levels to suppress feeding and mediate weight loss in common forms of obesity defines a state of so-called leptin resistance....
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ژورنال
عنوان ژورنال: Russian journal of Cardiology
سال: 2015
ISSN: 1560-4071
DOI: 10.15829/1560-4071-2015-4-107-110